Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.

The structure of the Staphylococcus aureus alpha-hemolysin pore has been determined to 1.9 A resolution. Contained within the mushroom-shaped homo-oligomeric heptamer is a solvent-filled channel, 100 A in length, that runs along the sevenfold axis and ranges from 14 A to 46 A in diameter. The lytic,...

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Detalhes bibliográficos
Principais autores: Song, L, Hobaugh, MR, Shustak, C, Cheley, S, Bayley, J, Gouaux, J
Formato: Journal article
Idioma:English
Publicado em: 1996