Holliday junctions formed from human telomeric DNA

Cells have evolved inherent mechanisms, like homologous recombination (HR), to repair damaged DNA. However, repairs at telomeres can lead to genomic instability, often associated with cancer. While most rapidly dividing cells employ telomerase, the others maintain telomere length through HR-dependen...

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Bibliographic Details
Main Authors: Haider, S, Li, P, Khiali, S, Munnur, D, Ramanathan, A, Parkinson, G
Format: Journal article
Language:English
Published: American Chemical Society 2018