Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1.

Humoral immune responses are thought to be enhanced by complement-mediated recruitment of the CD21-CD19-CD81 coreceptor complex into the B cell antigen receptor (BCR) complex, which lowers the threshold of B cell activation and increases the survival and proliferative capacity of responding B cells....

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Detalles Bibliográficos
Autores principales: Gatto, D, Pfister, T, Jegerlehner, A, Martin, S, Kopf, M, Bachmann, M
Formato: Journal article
Lenguaje:English
Publicado: 2005