Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors

Ionotropic glutamate receptors are functionally diverse but have a common architecture, including the 400-residue amino-terminal domain (ATD). We report a 1.8-Å resolution crystal structure of human GluR2-ATD. This dimeric structure provides a mechanism for how the ATDs can drive receptor assembly a...

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প্রধান লেখক: Clayton, A, Siebold, C, Gilbert, R, Sutton, G, Harlos, K, McIlhinney, R, Jones, E, Aricescu, A
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Elsevier 2009
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