V3: HIV's switch-hitter.

The third variable region, V3, of the gp120 surface envelope glycoprotein is an approximately 35-residue-long, frequently glycosylated, highly variable, disulfide-bonded structure that has a major influence on HIV-1 tropism. Thus the sequence of V3, directly or indirectly, can determine which corece...

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Bibliographic Details
Main Authors: Hartley, O, Klasse, P, Sattentau, Q, Moore, J
Format: Journal article
Language:English
Published: 2005