Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.

Míreanna comhchosúla

• The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis.
  de réir: Sacre, S, et al.
  Foilsithe / Cruthaithe: (2007)
• Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling.
  de réir: Sacre, S, et al.
  Foilsithe / Cruthaithe: (2007)
• Evidence for a DC-specific inhibitory mechanism that depends on MyD88 and SIGIRR.
  de réir: Drexler, S, et al.
  Foilsithe / Cruthaithe: (2010)
• VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
  de réir: Kiriakidis, S, et al.
  Foilsithe / Cruthaithe: (2003)
• VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
  de réir: Kiriakidis, S, et al.
  Foilsithe / Cruthaithe: (2003)