Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
MOTIVATION: The accuracy of reference genomes is important for downstream analysis but a low error rate requires expensive manual interrogation of the sequence. Here, we describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequenc...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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