Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.

MOTIVATION: The accuracy of reference genomes is important for downstream analysis but a low error rate requires expensive manual interrogation of the sequence. Here, we describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequenc...

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Detalles Bibliográficos
Main Authors: Otto, T, Sanders, M, Berriman, M, Newbold, C
Formato: Journal article
Idioma:English
Publicado: 2010