Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes

Posttranslational attachment of lipids to proteins is important for many cellular functions, and the enzymes responsible for these modifications are implicated in many diseases, from cancer to neurodegeneration. Lipid transferases and hydrolases are increasingly tractable therapeutic targets, but pr...

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Bibliographic Details
Main Authors: Lanyon-Hogg, T, Ritzefeld, M, Sefer, L, Bickel, J, Rudolf, A, Panyain, N, Bineva-Todd, G, Ocasio, C, O'Reilly, N, Siebold, C, Magee, A, Tate, E
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2019