The influence of bioreactor geometry and the mechanical environment on engineered tissues.
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. The cell population (and attendant extracellular matrix), culture medium, and porous scaffold are treated as distinct phases. The bioreactor system is represented by a two-dimensional channel containi...
Hauptverfasser: | Osborne, J, O'Dea, R, Whiteley, J, Byrne, H, Waters, S |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2010
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