High copy number in human endogenous retrovirus families is associated with copying mechanisms in addition to reinfection.
There are at least 31 families of human endogenous retroviruses (HERVs), each derived from an independent infection by an exogenous virus. Using evidence of purifying selection on HERV genes, we have shown previously that reinfection by replication-competent elements was the predominant mechanism of...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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