Exploration of P-type Ca2+ channels as drug targets for the treatment of epilepsy or ischemic stroke.

We investigated the neuroprotective efficacy of the P-type Ca2+ channel antagonist daurisoline against electroshock-induced convulsions in rats and mice, hypoxic/hypoglycemic-induced damage in rat hippocampal slices and brain damage induced by occlusion of the middle cerebral artery (MCA) in rats. D...

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Bibliographic Details
Main Authors: Lingenhöhl, K, Small, D, Monette, R, Buchan, A, Morley, P, Allegrini, P, Fröst, L, Sauer, D, Schmutz, M, Knöpfel, T
Format: Journal article
Language:English
Published: 1997