Mathematical modelling and transcriptional characterisation of intratumoral regulatory T cell sub-populations

<p>Regulatory T cells (Tregs) suppress harmful immune responses and help prevent autoimmune reactions. However, high densities of Tregs accumulate in solid tumours and contribute to the suppression of anti-tumor responses. The targeting of intratumoral Tregs via antibody-mediated blockade/depl...

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Bibliographic Details
Main Author: Muzhingi, I
Other Authors: Coles, M
Format: Thesis
Language:English
Published: 2023
Subjects: