Mathematical modelling and transcriptional characterisation of intratumoral regulatory T cell sub-populations
<p>Regulatory T cells (Tregs) suppress harmful immune responses and help prevent autoimmune reactions. However, high densities of Tregs accumulate in solid tumours and contribute to the suppression of anti-tumor responses. The targeting of intratumoral Tregs via antibody-mediated blockade/depl...
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Format: | Thesis |
Language: | English |
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2023
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