Mathematical modelling and transcriptional characterisation of intratumoral regulatory T cell sub-populations

Mathematical modelling and transcriptional characterisation of intratumoral regulatory T cell sub-populations

<p>Regulatory T cells (Tregs) suppress harmful immune responses and help prevent autoimmune reactions. However, high densities of Tregs accumulate in solid tumours and contribute to the suppression of anti-tumor responses. The targeting of intratumoral Tregs via antibody-mediated blockade/depl...

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Dettagli Bibliografici
Autore principale:	Muzhingi, I
Altri autori:	Coles, M
Natura:	Tesi
Lingua:	English
Pubblicazione:	2023
Soggetti:	Computational Biology Computational Immunology Immuno-oncology

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