Mathematical modelling and transcriptional characterisation of intratumoral regulatory T cell sub-populations
<p>Regulatory T cells (Tregs) suppress harmful immune responses and help prevent autoimmune reactions. However, high densities of Tregs accumulate in solid tumours and contribute to the suppression of anti-tumor responses. The targeting of intratumoral Tregs via antibody-mediated blockade/depl...
Үндсэн зохиолч: | Muzhingi, I |
---|---|
Бусад зохиолчид: | Coles, M |
Формат: | Дипломын ажил |
Хэл сонгох: | English |
Хэвлэсэн: |
2023
|
Нөхцлүүд: |
Ижил төстэй зүйлс
-
Characterising CD8+ T cell transcriptomic and clonal consequences of immune checkpoint blockade for the treatment of cancer
-н: Watson, RA
Хэвлэсэн: (2023) -
Patient-Specific Cell Communication Networks Associate With Disease Progression in Cancer
-н: David L. Gibbs, зэрэг
Хэвлэсэн: (2021-08-01) -
In silico simulation of a clinical trial with anti-CTLA-4 and anti-PD-L1 immunotherapies in metastatic breast cancer using a systems pharmacology model
-н: Hanwen Wang, зэрэг
Хэвлэсэн: (2019-05-01) -
Neoadjuvant chemotherapy drives intratumoral T cells toward a proinflammatory profile in pancreatic cancer
-н: Max Heiduk, зэрэг
Хэвлэсэн: (2022-11-01) -
ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data
-н: James W Opzoomer, зэрэг
Хэвлэсэн: (2021-04-01)