Counterion-mediated enantioconvergent synthesis of axially chiral medium rings

There are few enantioconvergent reactions in which racemic substrates bearing multiple stereochemical features are converted into products with high levels of diastereo- and enantiocontrol. Here, we disclose a process for the highly enantio- and diastereoselective syntheses of medium ring lactams vi...

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Bibliographic Details
Main Authors: Du, J-Y, Balan, T, Claridge, TDW, Smith, MD
Format: Journal article
Language:English
Published: American Chemical Society 2022