The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression.

The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates the mRNA elongation capacity of RNA polymerase II (RNAPII) through controlling the nuclear activity of positive transcription elongation factor b (P-TEFb). Here, we demonstrate that the huma...

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Hlavní autoři: Egloff, S, Vitali, P, Tellier, M, Raffel, R, Murphy, S, Kiss, T
Médium: Journal article
Jazyk:English
Vydáno: EMBO Press 2017