The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression.

The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates the mRNA elongation capacity of RNA polymerase II (RNAPII) through controlling the nuclear activity of positive transcription elongation factor b (P-TEFb). Here, we demonstrate that the huma...

Full description

Bibliographic Details
Main Authors: Egloff, S, Vitali, P, Tellier, M, Raffel, R, Murphy, S, Kiss, T
Format: Journal article
Language:English
Published: EMBO Press 2017