Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy.

The childhood motor neuron disease spinal muscular atrophy (SMA) results from reduced expression of the survival motor neuron (SMN) gene. Previous studies using in vitro model systems and lower organisms have suggested that low levels of Smn protein disrupt prenatal developmental processes in lower...

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Bibliografiska uppgifter
Huvudupphovsmän: Murray, L, Lee, S, Bäumer, D, Parson, S, Talbot, K, Gillingwater, T
Materialtyp: Journal article
Språk:English
Publicerad: 2010