Carbene footprinting reveals binding interfaces of a multimeric membrane‐spanning protein

Mapping the interaction sites between membrane‐spanning proteins is a key challenge in structural biology. In this study a carbene‐footprinting approach was developed and applied to identify the interfacial sites of a trimeric, integral membrane protein, OmpF, solubilised in micelles. The diazirine‐...

Полное описание

Библиографические подробности
Главные авторы: Manzi, L, Barrow, A, Hopper, J, Kaminska, R, Kleanthous, C, Robinson, C, Moses, J, Oldham, N
Формат: Journal article
Язык:English
Опубликовано: Wiley‐VCH Verlag 2017