Circadian profiling in two mouse models of lysosomal storage disorders; Niemann Pick type-C and Sandhoff disease.

Sleep and circadian rhythm disruption is frequently associated with neurodegenerative disease, yet it is unclear how the specific pathology in these disorders leads to abnormal rest/activity profiles. To investigate whether the pathological features of lysosomal storage disorders (LSDs) influence th...

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Bibliographic Details
Main Authors: Richardson, K, Livieratos, A, Dumbill, R, Hughes, S, Ang, G, Smith, D, Morris, L, Brown, L, Peirson, S, Platt, F, Davies, K, Oliver, P
Format: Journal article
Language:English
Published: Elsevier 2016