Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study.

Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study.

Insulin-like growth factor-I (IGF-I) stimulates cell proliferation and can enhance the development of tumors in different organs. Epidemiologic studies have shown that an elevated level of circulating IGF-I is associated to increased risk of breast cancer as well as other cancers. Genetic variants a...

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Bibliographic Details
Main Authors: Canzian, F, McKay, J, Cleveland, R, Dossus, L, Biessy, C, Boillot, C, Rinaldi, S, Llewellyn, M, Chajès, V, Clavel-Chapelon, F, Téhard, B, Chang-Claude, J, Linseisen, J, Lahmann, P, Pischon, T, Trichopoulos, D, Trichopoulou, A, Zilis, D, Palli, D, Tumino, R, Vineis, P, Berrino, F, Bueno-de-Mesquita, H, Gils, v, Peeters, P
Format: Journal article
Language:English
Published: 2005

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