Population pharmacokinetic assessment of a new regimen of mefloquine used in combination treatment of uncomplicated falciparum malaria.

A fixed artesunate-mefloquine combination, comprising three daily doses of 8 mg of mefloquine/kg of body weight and 4 mg of artesunate/kg, has been developed recently. This study was designed to construct a population pharmacokinetic model describing this new dosage regimen of mefloquine given as lo...

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Bibliographic Details
Main Authors: Ashley, E, Stepniewska, K, Lindegårdh, N, Mcgready, R, Hutagalung, R, Hae, R, Singhasivanon, P, White, N, Nosten, F
Format: Journal article
Language:English
Published: 2006