Molecular dynamics study of water and Na⁺ ions in models of the pore region of the nicotinic acetylcholine receptor
The nicotinic acetylcholine receptor (nAChR) is an integral membrane protein that forms ligand-gated and cation-selective channels. The central pore is lined by a bundle of five approximately parallel M2 helices, one from each subunit. Candidate model structures of the solvated pore region of a homo...
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Format: | Journal article |
Language: | English |
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Elsevier
1997
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