Steered molecular dynamics simulations predict conformational stability of glutamate receptors.

The stability of protein-protein interfaces can be essential for protein function. For ionotropic glutamate receptors, a family of ligand-gated ion channels vital for normal function of the central nervous system, such an interface exists between the extracellular ligand binding...

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Bibliographic Details
Main Authors: Musgaard, M, Biggin, P
Format: Journal article
Language:English
Published: American Chemical Society 2016