Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data

<strong>Background<br></strong> In 2012, the World Health Organization (WHO) recommended single low-dose (SLD, 0.25 mg/kg) primaquine to be added as a Plasmodium (P.) falciparum gametocytocide to artemisinin-based combination therapy (ACT) without glucose-6-phosphate dehydrogenase...

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Main Authors: Stepniewska, K, Allen, EN, Humphreys, GS, Poirot, E, Craig, E, Kennon, K, Yilma, D, Bousema, T, Guerin, PJ, White, NJ, Price, RN, Raman, J, Martensson, A, Mwaiswelo, RO, Bancone, G, Bastiaens, GJH, Bjorkman, A, Brown, JM, D’Alessandro, U, Dicko, AA, El-Sayed, B, Elzaki, S-E, Eziefula, AC, Gonçalves, BP, Hamid, MMA, Kaneko, A, Kariuki, S, Khan, W, Kwambai, TK, Ley, B, Ngasala, BE, Nosten, F, Okebe, J, Samuels, AM, Smit, MR, Stone, WJR, Sutanto, I, Ter Kuile, F, Tine, RC, Tiono, AB, Drakeley, CJ, Gosling, R, Stergachis, A, Barnes, KI, Chen, I
Format: Journal article
Language:English
Published: BioMed Central 2022