CRISPRing for host genes regulating SARS-CoV-2

In this preprint, Wei et al. screened the African green monkey genome using CRISPR–Cas9 for genes involved in SARS-CoV-2 infection and cell death. Surprisingly, SARS-CoV-2, which replicates in the cytosol, depends on a large number of host genes that function in the nucleus. Amongst the crucial gene...

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Bibliographic Details
Main Authors: Lu, F, Tellier, M
Format: Journal article
Language:English
Published: Nature Research 2020