Public health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience in The Netherlands.

A previous limited study demonstrated that Mycobacterium tuberculosis isolates with a mutation at amino-acid position 315 of katG (Delta315) exhibited high-level resistance to isoniazid and were more frequently resistant to streptomycin. In the present study, isoniazid-resistant M. tuberculosis isol...

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Bibliographic Details
Main Authors: Van Doorn, H, de Haas, P, Kremer, K, Vandenbroucke-Grauls, C, Borgdorff, M, van Soolingen, D
Format: Journal article
Language:English
Published: 2006