The role of group II metabotropic glutamate receptors in cognition and anxiety: comparative studies in GRM2(-/-), GRM3(-/-) and GRM2/3(-/-) knockout mice.

Group II metabotropic glutamate receptors (mGlu2 and mGlu3, encoded by GRM2 and GRM3) have been implicated in both cognitive and emotional processes, although their precise role remains to be established. Studies with knockout (KO) mice provide an important approach for investigating the role of spe...

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Bibliographic Details
Main Authors: De Filippis, B, Lyon, L, Taylor, A, Lane, T, Burnet, P, Harrison, P, Bannerman, D
Format: Journal article
Language:English
Published: Elsevier 2015