Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation.

Spatial relationships within the eukaryotic nucleus are essential for proper nuclear function. In Plasmodium falciparum, the repositioning of chromosomes has been implicated in the regulation of the expression of genes responsible for antigenic variation, and the formation of a single, peri-nuclear...

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Bibliographic Details
Main Authors: Lemieux, J, Kyes, SA, Otto, T, Feller, A, Eastman, RT, Pinches, R, Berriman, M, Su, X, Newbold, C
Format: Journal article
Language:English
Published: 2013