Reduction of electron-deficient pyrroles using group I and II metals in ammonia
The preparation and Birch reduction of a series of electron-deficient pyrroles is described. This methodology allows the synthesis of a variety of C-2 substituted 3-pyrrolines in good to excellent yields. The role of various activating groups (amide, ester, carbamate and urea) has been examined with...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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