Irreversibility of mitotic exit is the consequence of systems-level feedback.
The eukaryotic cell cycle comprises an ordered series of events, orchestrated by the activity of cyclin-dependent kinases (Cdks), leading from chromosome replication during S phase to their segregation in mitosis. The unidirectionality of cell-cycle transitions is fundamental for the successful comp...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
2009
|