Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice
Accumulating evidence points to an important role for the gut microbiome in anti-tumor immunity. Here, we show that altered intestinal microbiota contributes to anti-tumor immunity, limiting tumor expansion. Mice lacking the ubiquitin ligase RNF5 exhibit attenuated activation of the unfolded protein...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
Springer Nature Publishing Group
2019
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