Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase.
The selection of drug resistant virus is a significant obstacle to the continued successful treatment of HIV infection. Reverse transcriptase is the target for numerous approved anti-HIV drugs including both nucleoside inhibitor (NRTI) and non-nucleosides (NNRTI). The many available crystal structur...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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