SYNTHESIS OF, AND LACK OF INHIBITION OF A RHAMNOSIDASE BY, BOTH ENANTIOMERS OF DEOXYRHAMNOJIRIMYCIN AND RHAMNONOLACTAM - BETA-MANNOSIDASE INHIBITION BY DELTA-LACTAMS

Synthesis of both enantiomers of deoxyrhamnojirimycin and rhamnonolactam from D- and L-gulonolactones are described. The effects as inhibitors of the enantiomeric deoxyrhamnojirimycins and rhamnonolactams on human liver glycosidases are compared with deoxymannojirimycin and mannonolactam. No signifi...

Full description

Bibliographic Details
Main Authors: Fairbanks, A, Carpenter, N, Fleet, G, Ramsden, N, Debello, I, Winchester, B, Aldaher, S, Nagahashi, G
Format: Journal article
Language:English
Published: 1992