Structural studies of benzophenone/HIV-1 RT complexes: insights into the potency of the next generation NNRTls against WT and mutant HIV-1

相似书籍

• Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors.
  由: Ren, J, et al.
  出版: (2008)
• Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor.
  由: Romines, K, et al.
  出版: (2006)
• Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor.
  由: Romines, K, et al.
  出版: (2006)
• Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases.
  由: Ren, J, et al.
  出版: (2007)
• Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.
  由: Ren, J, et al.
  出版: (2004)