Targeting DNA repair nucleases in cancer
<p>The human enzyme Apollo/SNM1B is a 5′-3′ exonuclease implicated in two aspects of genome integrity, both the response to DNA damage, where it is proposed to play a role in double-strand break (DSB) and interstrand crosslink (ICL) repair and telomere maintenance, where it resects leading str...
| 主要作者: | |
|---|---|
| 其他作者: | |
| 格式: | Thesis |
| 語言: | English |
| 出版: |
2023
|
| 主題: |