Targeting DNA repair nucleases in cancer
<p>The human enzyme Apollo/SNM1B is a 5′-3′ exonuclease implicated in two aspects of genome integrity, both the response to DNA damage, where it is proposed to play a role in double-strand break (DSB) and interstrand crosslink (ICL) repair and telomere maintenance, where it resects leading str...
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| Médium: | Diplomová práce |
| Jazyk: | English |
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2023
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