Targeting DNA repair nucleases in cancer

<p>The human enzyme Apollo/SNM1B is a 5′-3′ exonuclease implicated in two aspects of genome integrity, both the response to DNA damage, where it is proposed to play a role in double-strand break (DSB) and interstrand crosslink (ICL) repair and telomere maintenance, where it resects leading str...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Henderson, LR
Awduron Eraill: McHugh, P
Fformat: Traethawd Ymchwil
Iaith:English
Cyhoeddwyd: 2023
Pynciau: