Targeting DNA repair nucleases in cancer
<p>The human enzyme Apollo/SNM1B is a 5′-3′ exonuclease implicated in two aspects of genome integrity, both the response to DNA damage, where it is proposed to play a role in double-strand break (DSB) and interstrand crosslink (ICL) repair and telomere maintenance, where it resects leading str...
מחבר ראשי: | |
---|---|
מחברים אחרים: | |
פורמט: | Thesis |
שפה: | English |
יצא לאור: |
2023
|
נושאים: |