Targeting DNA repair nucleases in cancer

<p>The human enzyme Apollo/SNM1B is a 5′-3′ exonuclease implicated in two aspects of genome integrity, both the response to DNA damage, where it is proposed to play a role in double-strand break (DSB) and interstrand crosslink (ICL) repair and telomere maintenance, where it resects leading str...

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Библиографические подробности
Главный автор: Henderson, LR
Другие авторы: McHugh, P
Формат: Диссертация
Язык:English
Опубликовано: 2023
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