Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction.
Sequence database searches, using iterative-profile and Hidden-Markov-model approaches, were used to detect hitherto-undetected homologues of proteins that regulate the endoplasmic reticulum (ER)-associated degradation pathway. The translocon-associated subunit Sec63p (Sec=secretory) was shown to co...
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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