A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis

Tuberculous meningitis has high mortality, linked to excessive inflammation. However, adjunctive anti-inflammatory corticosteroids reduce mortality by only 30%, suggesting that inflammatory pathophysiology causes only a subset of deaths. In Vietnam, the survival benefit of anti-inflammatory corticos...

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Bibliographic Details
Main Authors: Whitworth, L, Coxon, J, van Laarhoven, A, Thuong, NTT, Dian, S, Alisjahbana, B, Ganiem, AR, van Crevel, R, Thwaites, GE, Troll, M, Edelstein, PH, Sewell, R, Ramakrishnan, L
Format: Journal article
Language:English
Published: eLife Sciences Publications 2021