Patient-based transcriptome-wide analysis identify interferon and ubiquination pathways as potential predictors of influenza a disease severity

Background The influenza A virus is an RNA virus that is responsible for seasonal epidemics worldwide with up to five million cases of severe illness and 500,000 deaths annually according to the World Health Organization estimates. The factors associated with severe diseases are not well defined, bu...

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Main Authors: Hoang, LT, Tolfvenstam, T, Ooi, E, Khor, C, Naim, A, Ho, E, Ong, S, Wertheim, H, Fox, A, Van Vinh Nguyen, C, Nghiem, N, Ha, T, Thi Ngoc Tran, A, Tambayah, P, Lin, R, Sangsajja, C, Manosuthi, W, Chuchottaworn, C, Sansayunh, P, Chotpitayasunondh, T, Suntarattiwong, P, Chokephaibulkit, K, Puthavathana, P, Jong, D, Farrar, J, Van Doorn, H, Hibberd, M
Format: Journal article
Language:English
Published: Public Library of Science 2014