Asymmetric synthesis of alpha-alkylated aldehydes using terminal epoxide-derived chiral enamines.

Asymmetric synthesis of alpha-alkylated aldehydes using terminal epoxide-derived chiral enamines.

(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epoxide-enamine transformation provides the first enamines capable of generating α-alkylated aldehydes with high asymmetric induction by intermolecular nucleophilic substitution (see scheme). © 2008 Wile...

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Dettagli Bibliografici
Autori principali:	Hodgson, D, Kaka, N
Natura:	Journal article
Lingua:	English
Pubblicazione:	John Wiley and Sons 2008

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