Asymmetric synthesis of alpha-alkylated aldehydes using terminal epoxide-derived chiral enamines.
(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epoxide-enamine transformation provides the first enamines capable of generating α-alkylated aldehydes with high asymmetric induction by intermolecular nucleophilic substitution (see scheme). © 2008 Wile...
主要な著者: | Hodgson, D, Kaka, N |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
John Wiley and Sons
2008
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