The human lysozyme promoter directs reporter gene expression to activated myelomonocytic cells in transgenic mice.

The 5' region of the human lysozyme gene from -3500 to +25 was fused to a chloramphenicol acetyltransferase (CAT) reporter gene and three transgenic founder mice were obtained. All three transgenic lines showed the same pattern of CAT enzyme expression in adult mouse tissues that was consistent...

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Bibliographic Details
Main Authors: Clarke, S, Greaves, D, Chung, L, Tree, P, Gordon, S
Format: Journal article
Language:English
Published: 1996