Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.

The characterization of heterogeneous multicomponent protein complexes, which goes beyond identification of protein subunits, is a challenging task. Here we describe and apply a comprehensive method that combines a mild affinity purification procedure with a multiplexed mass spectrometry approach fo...

詳細記述

書誌詳細
主要な著者: Synowsky, SA, van den Heuvel, R, Mohammed, S, Pijnappel, P, Heck, A
フォーマット: Journal article
言語:English
出版事項: 2006