Pumping Ca2+ up H+ gradients: a Ca2+-H+ exchanger without a membrane

Cellular processes are exquisitely sensitive to H+ and Ca2+ ions because of powerful ionic interactions with proteins. By regulating the spatial and temporal distribution of intracellular [Ca2+] and [H+], cells such as cardiac myocytes can exercise control over their biological function. A well-esta...

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Bibliographic Details
Main Authors: Swietach, P, Leem, C, Spitzer, K, Vaughan-Jones, R
Format: Journal article
Published: Wiley 2014