Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells.

BACKGROUND: Archival formalin-fixed paraffin-embedded (FFPE) tissues have limited utility in applications involving analysis of gene expression due to mRNA degradation and modification during fixation and processing. This study analyzed 160 miRNAs in paired snap frozen and FFPE cells to investigate...

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Bibliographic Details
Main Authors: Li, J, Smyth, P, Flavin, R, Cahill, S, Denning, K, Aherne, S, Guenther, S, O'Leary, J, Sheils, O
Format: Journal article
Language:English
Published: 2007